Lys-Arg-Thr-Leu-Arg-Arg

Catalog No.: A28801
Hexapeptide
Lys-Arg-Thr-Leu-Arg-Arg (KRTLRR) is a hexapeptide that serves as a substrate for protein kinase C (PKC) derived from the epidermal growth factor receptor (EGFR). This compound is instrumental in studying PKC activity, enabling researchers to elucidate its role in various signaling pathways. Research applications include assessing the enzymatic function of PKC and exploring its implications in cellular processes such as proliferation and differentiation.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionLys-Arg-Thr-Leu-Arg-Arg (KRTLRR) is a hexapeptide that serves as a substrate for protein kinase C (PKC) derived from the epidermal growth factor receptor (EGFR). This compound is instrumental in studying PKC activity, enabling researchers to elucidate its role in various signaling pathways. Research applications include assessing the enzymatic function of PKC and exploring its implications in cellular processes such as proliferation and differentiation.
Product Information
Catalog NumA28801
FormulaC34H68N16O8
Molecular Weight829.01
CAS Number121284-21-7
SequenceLys-Arg-Thr-Leu-Arg-Arg
Sequence shorteningKRTLRR
SMILES[C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CCCCN)N)=O)CCCNC(=N)N)=O)[C@@H](C)O)=O)CC(C)C)=O)(C(N[C@@H](CCCNC(=N)N)C(O)=O)=O)CCCNC(=N)N
SynonymsKRTLRR
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