Fig. 1 · Structure
Documents & Downloads
Lys(CO-C3-p-I-Ph)-O-tBu
PK Modifier
Lys(CO-C3-p-I-Ph)-O-tBu is a pharmacokinetic modifier that enhances the pharmacokinetic properties of prostate-specific membrane antigen (PSMA) ligand molecules. By increasing the binding affinity to serum albumin, this compound prolongs the residence time of PSMA ligands in plasma. Additionally, it reduces uptake in the salivary glands, which may contribute to an extended half-life of the active compound, making it valuable for research in drug delivery and molecular imaging applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Ligand / Binder |
| CAS Number | 2703051-80-1 |
| Applications | PK Modifier |
| Formula | C20H31IN2O3 |
| Molecular Weight | 474.38 |
| SMILES | IC1=CC=C(CCCC(NCCCC[C@@H](C(OC(C)(C)C)=O)N)=O)C=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.