[Lys8, Lys9]-Neurotensin (8-13) is a neurotensin analog that primarily activates the G protein-coupled receptors NTS1 and NTS2. This compound demonstrates potent analgesic activity, with binding affinities (Ki values) of 0.33 nM and 0.95 nM for the human NTS1 and NTS2 receptors, respectively. It is utilized in research applications investigating pain modulation and neuropeptide signaling pathways.
[Lys8, Lys9]-Neurotensin (8-13) is a neurotensin analog that primarily activates the G protein-coupled receptors NTS1 and NTS2. This compound demonstrates potent analgesic activity, with binding affinities (Ki values) of 0.33 nM and 0.95 nM for the human NTS1 and NTS2 receptors, respectively. It is utilized in research applications investigating pain modulation and neuropeptide signaling pathways.
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