Fig. 1 · Structure

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Lyso-Monosialoganglioside GM3

Analogue of Ganglioside GM3

Lyso-Monosialoganglioside GM3 is an analogue of Ganglioside GM3 that primarily targets EGF signaling pathways. This compound exhibits antitumor activity by inhibiting EGF-induced increases in EGFR kinase activity in A431 epithelial cancer cells. It serves as a valuable tool for studying the role of gangliosides in cancer biology and exploring potential therapeutic strategies against epithelial tumors.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 94458-63-6
Applications Analogue of Ganglioside GM3
Formula C41H74N2O20
Molecular Weight 915.03
Synonyms Lyso-GM3
SMILES
OC([C@@]1(O[C@@]([C@@H]([C@H](C1)O)NC(C)=O)([H])[C@H](O)[C@H](O)CO)O[C@@H]2[C@H]([C@@H](O[C@@H]([C@@H]2O)CO)O[C@@H]3[C@H](O[C@H]([C@@H]([C@H]3O)O)OC[C@H](N)[C@H](O)/C=C/CCCCCCCCCCCCC)CO)O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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