Fig. 1 · Structure

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LZ9

CDK1/CDK2 Inhibitor

LZ9 is an ATP-competitive inhibitor of CDK1 and CDK2. This compound demonstrates significant biological activity in inhibiting cyclin-dependent kinases, making it a valuable tool for investigating cell cycle regulation. LZ9 has potential applications in research focused on colorectal cancer (CRC), aiding in the exploration of therapeutic strategies targeting this malignancy.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 844441-29-8
Applications CDK1/CDK2 Inhibitor
Formula C17H11F3N4O2
Molecular Weight 360.29
SMILES
O=C(C1=NNC=C1NC(C2=C(F)C=CC=C2F)=O)NC3=CC=C(C=C3)F

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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