Fig. 1 · Structure
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m-Iodobenzylguanidine sulfate
Norepinephrine Analogue
m-Iodobenzylguanidine sulfate (MIBG sulfate) is a norepinephrine analogue that exhibits significant antitumor activity. This compound is utilized as a radioiodinated radiopharmaceutical for the targeted diagnosis and treatment of adrenergic tumors. Additionally, m-Iodobenzylguanidine sulfate serves as a high-affinity substrate for cholera toxin, disrupting cellular mono(ADP-ribosylation) processes, making it valuable for various research applications in cellular biology and oncology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Substrate |
| CAS Number | 87862-25-7 |
| Applications | Norepinephrine Analogue |
| Formula | C8H10IN3.1/2H2O4S |
| Molecular Weight | 324.13 |
| Synonyms | MIBG sulfate; Iobenguane sulfate |
| SMILES | NC(NCC1=CC=CC(I)=C1)=N.O=S(O)(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.