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M-MoDE-A (2)

LYTACs

M-MoDE-A (2) is a bifunctional small molecule targeting the asialoglycoprotein receptor (ASGPR) to facilitate the degradation of extracellular proteins. This compound enables the selective delivery and destruction of specific proteins, making it a valuable tool in the study of protein turnover and cellular homeostasis. Its application in LYTAC (lysosome-targeting chimeras) research supports investigations into protein clearance pathways and potential therapeutic strategies for protein misfolding disorders.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2378837-56-8
Applications	LYTACs
Formula	C₇₈H₁₁₉FN₁₂O₃₄
Molecular Weight	1787.84
SMILES	CC(N[C@H]([C@H]([C@H]([C@H](O1)CO)O)O)[C@@H]1OCCOCCOCCNC(CCOCC(COCCC(NCCOCCOCCO[C@H]2[C@@H]([C@H]([C@H]([C@H](O2)CO)O)O)NC(C)=O)=O)(COCCC(NCCOCCOCCO[C@H]3[C@@H]([C@H]([C@H]([C@H](O3)CO)O)O)NC(C)=O)=O)NC(CNC(CCCOC4=CC5=C(C=C4)N=C(C6=CN(C7=CC(F)=C(C=C7)O)N=N6)C=C5)=O)=O)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.