M1001

Catalog No.: A19443
HIF-2α agonist
M1001 is a weak agonist of HIF-2α, directly binds to the HIF-2α PAS-B domain, with a Kd of 667 nM. M1001 enhances the stabilities of HIF-2α-ARNT complex.
Grouped product items
Product Name Price Stock Qty
M1001 5mg
$162.00
In stock
M1001 10mg
$279.00
In stock
M1001 50mg
$828.00
In stock
M1001 100mg
$1,656.00
In stock
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Biological Activity
Discription M1001 is a weak agonist of HIF-2α, directly binds to the HIF-2α PAS-B domain, with a Kd of 667 nM. M1001 enhances the stabilities of HIF-2α-ARNT complex.
Product Information
Catalog Num A19443
Formula C17H17N3O2S
Molecular Weight 327.4
CAS Number 874590-32-6
SMILES O=S1(C2=C(C=CC=C2)C(NC3=C(N4CCCC4)C=CC=C3)=N1)=O
Synonyms M 1001; M-1001
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 62 mg/mL (189.37 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 30.54 mL 152.72 mL 305.44 mL
0.5 mM 6.11 mL 30.54 mL 61.09 mL
1 mM 3.05 mL 15.27 mL 30.54 mL
5 mM 0.61 mL 3.05 mL 6.11 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

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This equation is commonly abbreviated as: C1V1 = C2V2

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