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M2I-1

Catalog No.: A12247

Mad2 inhibitor

M2I-1

M2I-1 Chemical Structure

CAS NO. 312271-03-7

M2I-1 is a Mad2 inhibitor targeting the binding of Mad2 to Cdc20, an essential protein-protein interaction (PPI) within the spindle assembly checkpoint (SAC).

Availability: In stock

Package Price Qty
2 mg
$90.00
5 mg
$180.00
10 mg
$350.00
50 mg
$1,030.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

M2I-1 is a Mad2 inhibitor targeting the binding of Mad2 to Cdc20, an essential protein-protein interaction (PPI) within the spindle assembly checkpoint (SAC).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.72 mL 123.62 mL 247.23 mL
0.5 mM 4.94 mL 24.72 mL 49.45 mL
1 mM 2.47 mL 12.36 mL 24.72 mL
5 mM 0.49 mL 2.47 mL 4.94 mL

*The above data is based on the productmolecular weight 404.48. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12247
Actions Inhibitor
CAS No. 312271-03-7
Formula C19H24N4O4S
M. Wt 404.48
Purity >98%
SMILES O=C(/C(C(N1)=O)=C\C2=CC=C(N(CC(C)C)CC(C)C)C([N+]([O-])=O)=C2)NC1=S
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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