Fig. 1 · Structure

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m3227G(5)ppp(5')A

mRNA Modification

m3227G(5)ppp(5')A is an mRNA molecule featuring a 3227-methylguanine (m3227G) cap, a triphosphate group, and an adenosine. This unique structure plays a crucial role in enhancing the stability and translation efficiency of mRNA. It is commonly utilized in research applications focusing on mRNA modification and gene expression studies.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 123212-19-1
Applications mRNA Modification
Formula C23H33N10O17P3
Molecular Weight 814.49
SMILES
O=C1C2=C(N([C@H]3[C@H](O)[C@H](O)[C@@H](COP(OP(OP(OC[C@H]4O[C@@H](N(C=N5)C6=C5C(N)=NC=N6)[C@H](O)[C@@H]4O)(O)=O)(O)=O)([O-])=O)O3)C=[N+]2C)NC(N(C)C)=N1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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