Fig. 1 · Structure

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M7G(3'-OMe-5')pppA(2'-OMe)

Cap Analogue

M7G(3'-OMe-5')pppA(2'-OMe) is a modified guanosine cap analogue, serving as a crucial substrate for in vitro mRNA synthesis. This compound mimics the natural mRNA cap structure, enhancing mRNA stability and translation efficiency. It is widely utilized in RNA research to facilitate the production of capped mRNA molecules for various applications, including gene expression studies and vaccine development.

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Specifications

Manufacturer Adooq Bioscience
Actions Substrate
CAS Number 3047739-39-6
Applications Cap Analogue
Formula C23H33N10O17P3
Molecular Weight 814.49
SMILES
NC1=NC=NC2=C1N=CN2[C@H]3[C@H](OC)[C@H](O)[C@@H](COP(OP(OP(OC[C@H]4O[C@@H](N(C=[N+]5C)C6=C5C(NC(N)=N6)=O)[C@H](O)[C@@H]4OC)([O-])=O)(O)=O)(O)=O)O3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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