Fig. 1 · Structure
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m7G(5')ppp(5')A diammonium
Cap Analog
m7G(5')ppp(5')A diammonium is a dinucleotide cap analog that mimics the natural 5' cap of eukaryotic mRNA. This compound is primarily utilized in in vitro RNA transcription studies to enhance the stability and translation efficiency of synthesized RNA transcripts. Its role as a cap analog makes it essential for researchers investigating RNA dynamics, translation mechanisms, and the development of RNA-based therapeutics.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 75252-10-7 |
| Applications | Cap Analog |
| Formula | C21H35N12O17P3 |
| Molecular Weight | 820.49 |
| Synonyms | m7GpppA diammonium; N7-Methyl-guanosine-5'-triphosphate-5'-adenosine diammonium |
| SMILES | O=P([O-])(OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C=NC(C2=NC=N3)=C3N)O1)OP(OP(OC[C@H]4O[C@@H](N5C(N=C(N6)N)=C([N+](C)=C5)C6=O)[C@H](O)[C@@H]4O)([O-])=O)([O-])=O.[NH4+].[NH4+] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.