Mabuterol is a selective beta-2 adrenergic receptor (ADRB2) agonist with oral bioavailability. This compound inhibits cell proliferation and effectively suppresses the rise of intracellular calcium levels triggered by PDGF-BB. Additionally, Mabuterol reduces protein expression of Drp-1, cyclin D1, and PCNA, while enhancing Mfn-2 expression in response to PDGF-BB. These properties make it a valuable tool for research into cellular proliferation and signaling pathways.
Mabuterol is a selective beta-2 adrenergic receptor (ADRB2) agonist with oral bioavailability. This compound inhibits cell proliferation and effectively suppresses the rise of intracellular calcium levels triggered by PDGF-BB. Additionally, Mabuterol reduces protein expression of Drp-1, cyclin D1, and PCNA, while enhancing Mfn-2 expression in response to PDGF-BB. These properties make it a valuable tool for research into cellular proliferation and signaling pathways.
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