Fig. 1 · Structure
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MAC-0547630
UppS Inhibitor
MAC-0547630 is a potent inhibitor of undecaprenyl diphosphate synthase (UppS), displaying IC50 values of 0.05 μM for UppSBS and 1.6 μM for UppSBA. This compound demonstrates significant antibacterial activity against Bacillus subtilis, with a minimum inhibitory concentration (MIC) of 0.1 ng/mL. MAC-0547630 serves as a valuable tool for research on bacterial cell wall synthesis and offers potential applications in antibiotic development.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 950386-41-1 |
| Applications | UppS Inhibitor |
| Formula | C19H21FN4 |
| Molecular Weight | 324.40 |
| SMILES | FC1=CC=C(C2=C(N=C(C)C=C3N4CCCCCC4)N3N=C2)C=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.