Fig. 1 · Structure
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Maceneolignan A
β-hexosaminidase Inhibitor
Maceneolignan A is a natural product that acts as a β-hexosaminidase inhibitor, isolated from the aril of Myristica fragrans. This compound effectively inhibits the release of β-hexosaminidase in RBL-2H3 cells, with an IC50 value of 48.4 μM. Additionally, Maceneolignan A demonstrates the capacity to inhibit TNF-α release in antigen-stimulated RBL-2H3 cells, exhibiting an IC50 of 63.7 μM. These properties make it a valuable tool for researching inflammatory responses and related pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1967042-42-7 |
| Applications | β-hexosaminidase Inhibitor |
| Formula | C21H24O5 |
| Molecular Weight | 356.41 |
| SMILES | COC1=C2C([C@H]([C@H](C3=CC(OC)=C(C(OC)=C3)O)O2)C)=CC(/C=C/C)=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.