Fig. 1 · Structure

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Mal-C2-amide-C10-tri-GalNAc

Asialoglycoprotein Receptor Binding Ligand Fragment

Mal-C2-amide-C10-tri-GalNAc is an asialoglycoprotein receptor (ASGPR) binding ligand fragment that plays a pivotal role in the development of lysosome-targeted bifunctional molecules. This compound facilitates the sequestration and lysosomal degradation of extracellular target molecules, making it valuable for studies focused on the mechanisms of autoimmune diseases and related therapeutic approaches. Researchers utilize Mal-C2-amide-C10-tri-GalNAc to explore receptor-mediated endocytosis and its implications in cellular processes.

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Specifications

Manufacturer Adooq Bioscience
Actions Ligand / Binder
CAS Number 2893765-20-1
Applications Asialoglycoprotein Receptor Binding Ligand Fragment
Formula C79H136N12O31
Molecular Weight 1749.99
SMILES
CC(N[C@H]([C@H]([C@H]([C@H](O1)CO)O)O)[C@@H]1OCCCCC(NCCCNC(CCOCC(COCCC(NCCCNC(CCCCO[C@H]2[C@@H]([C@H]([C@H]([C@H](O2)CO)O)O)NC(C)=O)=O)=O)(NC(CCCCCCCCCCC(NCCN3C(C=CC3=O)=O)=O)=O)COCCC(NCCCNC(CCCCO[C@H]4[C@@H]([C@H]([C@H]([C@H](O4)CO)O)O)NC(C)=O)=O)=O)=O)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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