Fig. 1 · Structure

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Mal-C5-Gly-Gly-Phe-MMAE

Drug-Linker Conjugate

Mal-C5-Gly-Gly-Phe-MMAE is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications. This compound combines the potent cytotoxic agent MMAE with a specialized linker, facilitating targeted delivery to cancer cells. Mal-C5-Gly-Gly-Phe-MMAE is primarily utilized in the synthesis of ADCs, aiding in the development of innovative cancer therapies and advancing cancer research.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 3056230-14-6
Applications Drug-Linker Conjugate
Formula C68H104N10O14
Molecular Weight 1285.61
SMILES
O[C@@H](C1=CC=CC=C1)[C@@H](C)NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C([C@H](CC(C)C)NC([C@@H](NC(CNC(CNC(CCCCCN3C(C=CC3=O)=O)=O)=O)=O)CC4=CC=CC=C4)=O)=O)=O)=O)=O)OC)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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