Fig. 1 · Structure
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Mal-GGFG-PAB-MMAE
Drug-Linker Conjugate
Mal-GGFG-PAB-MMAE is a drug-linker conjugate designed for targeted cancer therapy. Comprising the mitotic inhibitor MMAE linked via Mal-GGFG-PAB, this compound facilitates the selective delivery of cytotoxic agents to tumor cells. It is primarily utilized in the synthesis of antibody-drug conjugates, enhancing therapeutic efficacy while minimizing off-target effects.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 3055607-18-3 |
| Applications | Drug-Linker Conjugate |
| Formula | C69H97N11O16 |
| Molecular Weight | 1336.57 |
| SMILES | O[C@@H](C1=CC=CC=C1)[C@@H](C)NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OCC3=CC=C(C=C3)NC(CNC([C@@H](NC(CNC(CNC(CCN4C(C=CC4=O)=O)=O)=O)=O)CC5=CC=CC=C5)=O)=O)=O)=O)=O)=O)OC)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.