Fig. 1 · Structure
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Mal-Gly-PAB-Exatecan-D-glucuronic acid
ADC Intermediate Compound
Mal-Gly-PAB-Exatecan-D-glucuronic acid serves as an intermediate compound in the synthesis of antibody-drug conjugates (ADCs). This compound facilitates the targeted delivery of cytotoxic agents to tumor cells, enhancing therapeutic efficacy while minimizing off-target effects. It is valuable for research applications related to tumor biology and cancer diagnostics.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2763252-25-9 |
| Applications | ADC Intermediate Compound |
| Formula | C47H45FN6O17 |
| Molecular Weight | 984.89 |
| SMILES | O=C(C=CC1=O)N1CCC(NCC(NC(C=C2COC(N[C@@H]3C4=C5C(C(N6C5)=CC([C@](O)(C(OC7)=O)CC)=C7C6=O)=NC8=CC(F)=C(C)C(CC3)=C84)=O)=C(C=C2)O[C@@H]9O[C@@H]([C@H]([C@@H]([C@H]9O)O)O)C(O)=O)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.