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Mal-PEG2-Val-Arg-PABC-OMe-Eribulin

Drug-linker Conjugate

Mal-PEG2-Val-Arg-PABC-OMe-Eribulin functions as a drug-linker conjugate, combining O-Me Eribulin with the linker Mal-PEG2-Val-Arg-PABC. This compound is designed for the synthesis of antibody-drug conjugates (ADCs) targeting the HER3 and MET pathways. Its biological activity enables targeted delivery of chemotherapeutic agents, enhancing the efficacy of cancer therapies while minimizing systemic toxicity. This reagent is valuable for researchers developing innovative ADC formulations in cancer treatment studies.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2676196-79-3
Applications	Drug-linker Conjugate
Formula	C₇₁H₁₀₁N₇O₂₁
Molecular Weight	1388.60
SMILES	C=C1C[C@](O[C@@]1([H])CC[C@](C[C@H]2C)([H])O[C@](C2=C)([H])C[C@@](O[C@@H]3C[C@H](OC)CNC(OCC(C=C4)=CC=C4NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCOCCOCCN(C5=O)C(C=C5)=O)=O)=O)=O)=O)([H])[C@]([C@H]3OC)([H])CC6=O)([H])CC[C@@]7(C[C@@]8([H])O9)O[C@]([C@](O[C@](C6)([H])CC%10)([H])[C@@]%10([H])O%11)([H])[C@@]9([H])[C@]%11([H])[C@@]8([H])O7

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.