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Mal-Val-Ala-PAB(C2-glucuronic acid)-DMEA-PNU-159682

ADC Active Molecule-Conjugate

Mal-Val-Ala-PAB(C2-glucuronic acid)-DMEA-PNU-159682 is an active molecule-conjugate designed for antibody-drug conjugate (ADC) applications. It features a cleavable Val-Ala linker, enabling the selective release of the potent cytotoxic agent PNU-159682. This compound is useful for research in targeted cancer therapies, facilitating the study of ADC efficacy and mechanism of action in preclinical models.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2682939-53-1
Applications	ADC Active Molecule-Conjugate
Formula	C₆₇H₈₁N₇O₂₇
Molecular Weight	1416.39
SMILES	OC1=C2C(C(C(C(OC)=CC=C3)=C3C2=O)=O)=C(O)C4=C1C[C@](C(COC(N(C)CCN(C)C(OCC5=CC=C(NC([C@H](C)NC([C@H](C(C)C)NC(CN6C(C=CC6=O)=O)=O)=O)=O)C=C5CC[C@H]7[C@H](O)[C@@H](O)[C@H](O)[C@@H](C(O)=O)O7)=O)=O)=O)(O)C[C@@H]4O[C@H]8C[C@H](N(CCO[C@@H]9OC)[C@@H]9O%10)[C@H]%10[C@H](C)O8

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.