Fig. 1 · Structure
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Mambalgin 1
Toxin
Mambalgin 1 is a toxin derived from the venom of the black mamba, featuring a disulfide-rich structure of 57 amino acids. This polypeptide belongs to the three-finger toxin family and exhibits high-affinity binding to acid-sensing ion channels (ASICs), stabilizing them in a physiologically relevant closed-state conformation. Mambalgin 1's ability to modulate ASIC activity makes it a valuable tool for research in pain pathways and neurobiology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1609937-15-6 |
| Applications | Toxin |
| Formula | C272H429N85O84S10 |
| Molecular Weight | 6554.54 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.