Fig. 1 · Structure

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Manidipine-d4

Stable Isotope

Manidipine-d4 is a deuterated form of Manidipine, a calcium channel antagonist with oral bioavailability. It exerts hypotensive effects and modulates the expression of cytokines, such as IL-1β and IL-6. This reagent is applicable in the investigation of cardiovascular conditions, including hypertension and myocardial ischemia-reperfusion injury, as well as in renal pathologies and epilepsy research.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 1189656-59-4
Applications Stable Isotope
Formula C35H34D4N4O6
Molecular Weight 614.72
SMILES
C(OC(C(N1CCN(C(C2=CC=CC=C2)C3=CC=CC=C3)CC1)([2H])[2H])([2H])[2H])(=O)C=4C(C(C(OC)=O)=C(C)NC4C)C5=CC(N(=O)=O)=CC=C5

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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