Fig. 1 · Structure

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MANT-cGMP

Adenylyl Cyclase Inhibitor

MANT-cGMP is an adenylyl cyclase inhibitor with a Ki value of 100 μM and a pKi of 4. This ribose-substituted nucleotide is valuable for investigating physiological processes and pathological conditions associated with heart failure, cancer, and neurological disorders. Its ability to inhibit adenylyl cyclase activity makes MANT-cGMP a useful tool for elucidating signaling pathways and exploring therapeutic interventions in related research areas.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 83707-15-7
Applications Adenylyl Cyclase Inhibitor
Formula C18H19N6O8P
Molecular Weight 478.35
SMILES
O=C(C(C=CC=C1)=C1NC)O[C@H]2[C@@](N3C(NC(N)=NC4=O)=C4N=C3)([H])O[C@@](CO5)([H])[C@@]2([H])O[P]5(O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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