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MAT2A-IN-16

MAT2A Inhibitor

MAT2A-IN-16 is a selective inhibitor of methionine adenosyltransferase 2A (MAT2A), demonstrating significant inhibition of cell proliferation in MTAP-deficient HCT-116 cells with an IC50 of 20 nM. This compound serves as a valuable tool for investigating the role of MAT2A in cancer biology and may aid in the development of novel therapeutic strategies targeting MAT2A-related pathways.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3025016-60-5
Applications	MAT2A Inhibitor
Formula	C₂₃H₁₇ClN₆O
Molecular Weight	428.87
SMILES	O=C1N=C2C3=C(CN2C4=CC5=CN(C)N=C5C=C4)C=C(Cl)C=C3N1C6=CC=CN=C6C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.