Documents & Downloads

MAT2A-IN-22

MAT2A Inhibitor

MAT2A-IN-22 is a potent inhibitor of methionine adenosyltransferase 2A (MAT2A), with an IC50 value of 4 nM. This compound is capable of penetrating the blood-brain barrier and demonstrates selective inhibitory effects on MTAP-deficient cancer cell lines. MAT2A-IN-22 exhibits notable anti-tumor activity, making it a valuable tool for cancer research and therapeutic development.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2925330-18-1
Applications	MAT2A Inhibitor
Formula	C₁₈H₁₁D₃F₃N₃O
Molecular Weight	348.34
SMILES	O=C1[C@]2(C3=CC(C(F)(F)F)=CC=C3C(NC([2H])([2H])[2H])=N1)C4=CC=CN=C4CC2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.