Fig. 1 · Structure
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MAT2A inhibitor 5
MAT2A Inhibitor
MAT2A Inhibitor 5 is a selective inhibitor of methionine adenosyltransferase 2A (MAT2A) demonstrating an IC50 of 11 nM. This compound exhibits oral bioavailability and effective blood-brain barrier permeability, making it suitable for in vivo applications. MAT2A Inhibitor 5 is intended for research on tumor growth inhibition and the role of MAT2A in various cancer models.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2957874-18-7 |
| Applications | MAT2A Inhibitor |
| Formula | C19H14ClFN4O |
| Molecular Weight | 368.79 |
| SMILES | O=C1N(C2=CC(Cl)=C(C=C2C3=CN(N=C13)C)F)C4=CC=CN=C4C5CC5 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.