Fig. 1 · Structure

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MAT2A inhibitor 6

MAT2A Inhibitor

MAT2A inhibitor 6 is a selective inhibitor targeting methionine adenosyltransferase 2A (MAT2A) with an IC50 of 26 nM. This compound exhibits yellow fluorescence, allowing for the visualization of MAT2A activity in both in vitro and in vivo settings (λex = 430 nm, λem = 585 nm). MAT2A inhibitor 6 has demonstrated the ability to induce apoptosis and possesses significant anticancer properties, making it a valuable tool in cancer research applications.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2447686-21-5
Applications MAT2A Inhibitor
Formula C24H19F2N5O3
Molecular Weight 463.44
SMILES
O=C1C(C2=CC=C(OC(F)F)C=C2)=C3C(C=CC(OCC)=N3)=NN1C4=CC5=CN(C)N=C5C=C4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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