Fig. 1 · Structure
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MAX-10181
PD-1/PD-L1 Inhibitor
MAX-10181 is a selective inhibitor of the PD-1/PD-L1 interaction, exhibiting an IC50 value of 0.018 μM. This compound is instrumental in cancer research, facilitating the exploration of immune checkpoint blockade mechanisms and potential therapeutic applications in oncology and related diseases. Researchers can utilize MAX-10181 to study the modulation of immune responses in various tumor models.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2171558-14-6 |
| Applications | PD-1/PD-L1 Inhibitor |
| Formula | C29H28F3NO5 |
| Molecular Weight | 527.53 |
| Synonyms | PD-1/PD-L1-IN-30 |
| SMILES | CC1=C(C=CC=C1/C=C/C2=C(C=CC(CNC(CO)(C)C(O)=O)=C2)C(F)(F)F)C3=CC=C(OCCO4)C4=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.