Documents & Downloads

Maxadilan

PAC1-Receptor Agonist

Maxadilan is a specific irreversible agonist of the PAC1 receptor, known for its potent vasodilatory effects. This peptide, derived from the salivary glands of sand flies, exhibits significant anti-apoptotic properties in human adipose-derived stem cells (hADSCs) and modulates inflammatory responses by inhibiting pro-inflammatory cytokines such as TNF-α while enhancing anti-inflammatory mediators like IL-10. Additionally, Maxadilan facilitates leukocyte activation and decreases vascular permeability through PAC1 receptor engagement. It serves as a valuable tool in research related to endotoxin shock, atherosclerosis, and neurodegenerative diseases.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
Actions	Agonist
CAS Number	135374-80-0
Applications	PAC1-Receptor Agonist
Formula	C₂₉₁H₄₆₆N₈₆O₉₄S₆
Molecular Weight	6865.72

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.