Fig. 1 · Structure
Documents & Downloads
MBM-17S
Nek2 Inhibitor
MBM-17S is a highly potent inhibitor of NIMA-related kinase 2 (Nek2) with an IC50 of 3 nM. This compound demonstrates significant antiproliferative effects on cancer cells by promoting cell cycle arrest and inducing apoptosis. MBM-17S exhibits notable antitumor activities while maintaining a favorable safety profile in murine models. Its ability to target Nek2 makes it a valuable reagent for cancer research and therapeutic studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2083621-91-2 |
| Applications | Nek2 Inhibitor |
| Formula | C36H40N6O10 |
| Molecular Weight | 716.74 |
| SMILES | O=C(O)CCC(O)=O.O=C(O)CCC(O)=O.NC(C(C=C1)=C(OCC2=CC=CC=C2)C=C1C3=CN=C4N3C=CC(C5=CN(CCN(C)C)N=C5)=C4)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.