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MC-amide-C2-amide-(β-D-GlcUA)-amide-PEG1-CH2-CC-885

CC-885-Linker Coupling

MC-amide-C2-amide-(β-D-GlcUA)-amide-PEG1-CH2-CC-885 is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications. This compound links CC-885 with a tailored PEG-based linker and demonstrates potent anti-tumor activity in preclinical models. Specifically, it facilitates the synthesis of ADC-2 with Gemtuzumab, which has shown efficacy in a leukemia MV-4-11 xenograft model. This reagent is suitable for research applications focusing on targeted cancer therapies.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2874334-41-3
Applications	CC-885-Linker Coupling
Formula	C₅₃H₆₁ClN₈O₁₈
Molecular Weight	1133.55
SMILES	O=C1N(C2C(NC(CC2)=O)=O)CC3=CC(CNC(NC4=CC(Cl)=C(C=C4)CCOCCN(C)C(OCC5=CC(C(NCCNC(CCCCCN6C(C=CC6=O)=O)=O)=O)=C(C=C5)O[C@@H]7O[C@@H]([C@H]([C@@H]([C@H]7O)O)O)C(O)=O)=O)=O)=CC=C31

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.