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MC-GGFG-AM-(10NH2-11F-Camptothecin)

Antibody Drug Conjugates

MC-GGFG-AM-(10NH2-11F-Camptothecin) is an antibody-drug conjugate (ADC) designed for targeted cancer therapy. It effectively binds to the anti-TROp-2 antibody sacituzumab through a hydrolysable pH-sensitive linker, exhibiting significant anti-tumor activity. This compound is suitable for cancer research, particularly in studies focused on ADC mechanisms and therapeutic efficacy.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2987938-97-4
Applications	Antibody Drug Conjugates
Formula	C₄₅H₄₅FN₈O₁₁
Molecular Weight	892.88
SMILES	O=C1N2C(C(C(C2)=CC3=C4)=NC3=CC(F)=C4NC(CNC([C@@H](NC(CNC(CNC(CCCCCN5C(C=CC5=O)=O)=O)=O)=O)CC6=CC=CC=C6)=O)=O)=CC7=C1COC([C@]7(O)CC)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.