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MC-Val-Cit-Gly-exatecan-β-D-glucopyranosiduronic acid

Drug-Linker Conjugate

MC-Val-Cit-Gly-exatecan-β-D-glucopyranosiduronic acid is a drug-linker conjugate designed to deliver the DNA topoisomerase I inhibitor, Exatecan. This compound features a Val-Cit-Gly peptide linker, facilitating targeted delivery for antibody-drug conjugates (ADCs). It is primarily utilized in the synthesis of ADCs, enhancing therapeutic efficacy in cancer research by promoting selective cytotoxicity against tumor cells.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	3023709-42-1
Applications	Drug-Linker Conjugate
Formula	C₅₃H₆₃FN₈O₁₉
Molecular Weight	1135.11
SMILES	OC([C@H]([C@H]([C@@H]([C@H]1O)O)O)O[C@H]1OC[C@H](NC([C@H](C(C)C)NC(CCCCCN2C(C=CC2=O)=O)=O)=O)C(NCC(NCOCC(N[C@@H]3C4=C5C(C(N6C5)=CC([C@](O)(C(OC7)=O)CC)=C7C6=O)=NC8=CC(F)=C(C)C(CC3)=C84)=O)=O)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.