Fig. 1 · Structure

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MC2625

HDAC Inhibitor

MC2625 is a potent histone deacetylase (HDAC) inhibitor, specifically targeting HDAC3 and HDAC6 with IC50 values of 80 nM and 11 nM, respectively. This compound effectively increases levels of acetylated histone H3 and acetylated tubulin, promoting apoptosis in cancer stem cells (CSCs) and inhibiting their growth. MC2625 serves as a valuable tool for research focused on cancer therapeutics and the role of epigenetics in tumor biology.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 1776116-75-6
Applications HDAC Inhibitor
Formula C23H21N3O3
Molecular Weight 387.43
SMILES
O=C(NO)/C=C/C1=NC=C(C=C1)NC(C(C2=CC=CC=C2)CC3=CC=CC=C3)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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