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Biological Activity
MCHr1 antagonist 2 is an antagonist of melanin concentrating hormone receptor 1, with an IC50 of 65 nM; MCHr1 antagonist 2 also inhibits hERG, with an IC50 of 4.0 nM in IMR-32 cells.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.56 mL | 117.81 mL | 235.62 mL |
| 0.5 mM | 4.71 mL | 23.56 mL | 47.12 mL |
| 1 mM | 2.36 mL | 11.78 mL | 23.56 mL |
| 5 mM | 0.47 mL | 2.36 mL | 4.71 mL |
*The above data is based on the productmolecular weight 424.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A12379 |
|---|---|
| Actions | Antagonist |
| CAS No. | 863115-70-2 |
| Formula | C23H21FN2O5 |
| M. Wt | 424.42 |
| Purity | >98% |
| SMILES | O=C(C1=CC(C2=CC(F)=CC=C2O1)=O)NC3CCN(CC4=CC=C(OCO5)C5=C4)CC3 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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