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MCL-0129

Melanocortin Receptor Antagonist

MCL-0129 is a selective antagonist of the melanocortin 4 receptor (MC4R), known for its potential anxiolytic and antidepressant properties. This compound exhibits significant anxiolytic and antidepressant-like effects in various rodent models, making it a valuable tool for research into neuropsychiatric disorders. Its specific targeting of MC4R supports studies aimed at elucidating the mechanisms of action in stress-related and mood disorders.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Antagonist
CAS Number	768357-45-5
Applications	Melanocortin Receptor Antagonist
Formula	C₃₄H₄₇FN₄O
Molecular Weight	546.76
SMILES	COC1=C(C2=C(C=CC=C2)C=C1)CCCCN(CC3)CCN3C[C@H](C4=CC=C(C=C4)F)N5CCN(CC5)C(C)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.