MCL-1/BCL-2-IN-3

Catalog No.: A18385

Mcl-1 and Bcl-2 dual inhibitor

MCL-1/BCL-2-IN-3

MCL-1/BCL-2-IN-3 Chemical Structure

CAS NO. 2163793-55-1

MCL-1/BCL-2-IN-3 (Compound 2) is a potent and selective Mcl-1 and Bcl-2 dual inhibitor with IC50s of 5.95 and 4.78 μM, respectively.

Availability: In stock

Package Price Qty
1 mg
$120.00
5 mg
$350.00
10 mg
$650.00
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Biological Activity

MCL-1/BCL-2-IN-3 (Compound 2) is a potent and selective Mcl-1 and Bcl-2 dual inhibitor with IC50s of 5.95 and 4.78 μM, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.56 mL 87.8 mL 175.6 mL
0.5 mM 3.51 mL 17.56 mL 35.12 mL
1 mM 1.76 mL 8.78 mL 17.56 mL
5 mM 0.35 mL 1.76 mL 3.51 mL

*The above data is based on the productmolecular weight 569.47. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18385
Actions Inhibitor
CAS No. 2163793-55-1
Formula C27H25BrN2O5S
M. Wt 569.47
Purity >98%
SMILES O=C(OC)CCCCC(NCCN(C(C1=CC=C(SC2=CC=C(Br)C=C2)C3=CC=CC4=C13)=O)C4=O)=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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