Mcl1-IN-11

Catalog No.: A18377

Mcl-1 inhibitor

Mcl1-IN-11

Mcl1-IN-11 Chemical Structure

CAS NO. 2042211-13-0

Mcl1-IN-11 (Compound G) is a selective Mcl-1 inhibitor, less potent at Bcl-2, with Kis of 0.06 and 4.2 μM, respectively.

Availability: In stock

Package Price Qty
5 mg
$350.00
10 mg
$650.00
50 mg
$2,000.00
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Biological Activity

Mcl1-IN-11 (Compound G) is a selective Mcl-1 inhibitor, less potent at Bcl-2, with Kis of 0.06 and 4.2 μM, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 14.62 mL 73.11 mL 146.22 mL
0.5 mM 2.92 mL 14.62 mL 29.24 mL
1 mM 1.46 mL 7.31 mL 14.62 mL
5 mM 0.29 mL 1.46 mL 2.92 mL

*The above data is based on the productmolecular weight 683.88. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18377
Actions Inhibitor
CAS No. 2042211-13-0
Formula C38H41N3O5S2
M. Wt 683.88
Solubility DMSO
Purity >98%
SMILES CC1(C)C2=CC(C)=C(C(C3=CC=C(C(NS(=O)(C4=CC=C(NCCSC5=CC=CC=C5)C([N+]([O-])=O)=C4)=O)=O)C=C3)=C)C=C2C(C)(C)CC1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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