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Mcl1-IN-14

Mcl1-IN-14 is a reversible covalent inhibitor targeting the anti-apoptotic protein Mcl-1. This compound exhibits potent inhibitory activity by covalently modifying the non-catalytic lysine side chain of Mcl-1, demonstrating superior efficacy compared to non-covalent inhibitors. Mcl1-IN-14 is valuable for research applications focused on apoptosis regulation and the development of novel Mcl-1 inhibitory compounds to explore related biological processes.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2012563-29-8
Formula	C₃₅H₃₂BN₃O₇
Molecular Weight	617.46
SMILES	O=C(O)C(NC1=C2C=CC=C1C3=C(N(N=C3COC4=CC=C(C(C=O)=C4)B(O)O)C)C)=C2CCCOC5=C6C=CC=CC6=CC=C5

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.