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MCULE-3064932370

SUMO E1 Inhibitor

MCULE-3064932370 is a covalent and allosteric inhibitor of SUMO E1, targeting the heterodimer of Aos1 and Uba2. With IC50 values determined between 16.66 μM and 2.96 μM, it effectively inhibits the SUMOylation process of Uba2. This reagent demonstrates significant anti-cancer activity, particularly against breast cancer, making it valuable for research in cancer therapy and cellular regulation studies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	315698-78-3
Applications	SUMO E1 Inhibitor
Formula	C₁₈H₁₂N₂O₃S₂
Molecular Weight	368.43
SMILES	O=C(C(SC#N)=C/1)C2=CC=CC=C2C1=N\S(=O)(C3=CC=C(C)C=C3)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.