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MD01-67

NTS2 Activator

MD01-67 is a selective macrocyclic compound that acts as an activator of the neurotensin receptor type 2 (NTS2), with a binding affinity (Ki) of 2.9 nM. It demonstrates significant analgesic properties and effectively reduces tactile hypersensitivity in various rat models of acute, persistent, and chronic inflammatory pain. This compound is valuable for researchers studying pain mechanisms and developing new analgesic therapies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Activator
CAS Number	2468971-42-6
Applications	NTS2 Activator
Formula	C₃₇H₅₈N₈O₈
Molecular Weight	742.91
SMILES	[C@H](CC1=CC=C(O)C=C1)(C(N[C@@H](CC2CCCC2)C(O)=O)=O)NC(=O)[C@H]3NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CC=CC3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.