Documents & Downloads

(-)-MDO-NPA

D1R/D2R Ligand

(-)-MDO-NPA is a dual-target ligand for dopamine receptors D1R and D2R, functioning as an N-propylnorapomorphine analog. It demonstrates β-arrestin EC50 values of 1949 nM for D1R and 520 nM for D2R, and cAMP EC50 values of 717.5 nM for D1R and 7.7 nM for D2R. This compound is particularly valuable for studying dopamine-related disorders, including Parkinson's disease, and contributes to understanding receptor signaling pathways in pharmacological research.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	81264-57-5
Applications	D1R/D2R Ligand
Formula	C₂₀H₂₁NO₂
Molecular Weight	307.39
SMILES	CCCN1[C@@]2([H])C3=C(CC1)C=CC=C3C4=C(C2)C=CC5=C4OCO5

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.