Fig. 1 · Structure
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mDPR-Val-Cit-PAB-MMAE TFA
Intermediate
mDPR-Val-Cit-PAB-MMAE TFA is an advanced drug-linker conjugate designed for antibody-drug conjugate (ADC) applications. This compound integrates the tubulin polymerization inhibitor MMAE with a proprietary ADC linker composed of Val-Cit-PAB. It serves as an essential intermediate for the development of targeted therapies, facilitating effective delivery and release of cytotoxic agents within tumor cells. Researchers can utilize this reagent to enhance the specificity and efficacy of cancer treatments in preclinical studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2185872-76-6 |
| Applications | Intermediate |
| Formula | C67H101F3N12O17 |
| Molecular Weight | 1403.58 |
| SMILES | CC[C@H](C)[C@@H]([C@@H](CC(N1[C@@H](CCC1)[C@@H]([C@@H](C)C(N[C@H](C)[C@@H](O)C2=CC=CC=C2)=O)OC)=O)OC)N(C([C@H](C(C)C)NC([C@H](C(C)C)N(C(OCC3=CC=C(NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC([C@@H](N4C(C=CC4=O)=O)CN)=O)=O)=O)C=C3)=O)C)=O)=O)C.O=C(O)C(F)(F)F |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.