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ME-3277

GPIIb/IIIa Antagonist

ME-3277 is a potent GPIIb/IIIa antagonist that exhibits neuroprotective effects by significantly reducing cerebral infarction while avoiding the risk of enhancing intracranial hemorrhage in models of photothrombotic occlusion of the middle cerebral artery in rabbits. This compound is valuable for research focused on acute cerebral infarction, providing insights into therapeutic strategies for stroke management and prevention.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Antagonist
CAS Number	165948-72-1
Applications	GPIIb/IIIa Antagonist
Formula	C₂₀H₂₀N₂O₈S
Molecular Weight	448.45
SMILES	O=C(C1=CC=C(OCC(O)=O)C(OCC(O)=O)=C1)CNC(C(S2)=CC3=C2CCNC3)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.