Fig. 1 · Structure
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Meclonazepam (Ro 11-3128, Ro 11-3128/002)
Anxiolytic/Anti-schistosomal Agent
Meclonazepam, a benzodiazepine derivative, primarily functions as an anxiolytic and exhibits notable anti-schistosomal activity. It effectively targets immature Schistosoma mansoni, demonstrating complete elimination of parasites at a concentration of 30 μM. This compound serves as a valuable tool for research involving anxiety modulation and schistosomiasis treatment.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 58662-84-3 |
| Applications | Anxiolytic/Anti-schistosomal Agent |
| Formula | C16H12ClN3O3 |
| Molecular Weight | 329.74 |
| Synonyms | Ro 11-3128; Ro 11-3128/002 |
| SMILES | O=C1NC2=CC=C([N+]([O-])=O)C=C2C(C3=CC=CC=C3Cl)=N[C@H]1C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.