Fig. 1 · Structure

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MEDI-5884

Anti-EL Antibody

MEDI-5884 is a humanized IgG4Pκ monoclonal antibody that specifically targets Endothelial lipase (EL). This neutralizing antibody effectively inhibits EL activity, leading to an increased quantity and enhanced functionality of high-density lipoproteins (HDL), particularly in terms of phosphatidylinositols and cholesteryl esters. MEDI-5884 is applicable in cardiovascular research, especially in studies related to coronary artery disease (CAD).

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Specifications

Manufacturer Adooq Bioscience
CAS Number 2643310-75-0
Applications Anti-EL Antibody
Synonyms REG-101

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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