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MEDICA16

Acetyl-CoA Carboxylase/ATP-Citrate Lyase Inhibitor

MEDICA16 is a potent inhibitor of acetyl-CoA carboxylase and ATP-citrate lyase, targeting key enzymes involved in lipid metabolism. By limiting the availability of acetyl-CoA for acetyl-CoA carboxylase and exerting competitive inhibition on ATP-citrate lyase, MEDICA16 effectively reduces hepatic AMPK activity. This compound is valuable for research in areas such as insulin resistance, hyperlipidemia, and obesity, providing insights into metabolic disorders and potential therapeutic approaches.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	87272-20-6
Applications	Acetyl-CoA Carboxylase/ATP-Citrate Lyase Inhibitor
Formula	C₂₀H₃₈O₄
Molecular Weight	342.51
SMILES	O=C(O)CC(C)(C)CCCCCCCCCCC(C)(C)CC(O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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MEDICA16

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MEDICA16 5 mg