Fig. 1 · Structure
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Mefatinib free base
Tyrosine Kinase Inhibitor
Mefatinib free base is a selective tyrosine kinase inhibitor that exhibits significant anti-cancer activity. It primarily functions by inhibiting the enzymatic activity of key signaling pathways involved in tumor proliferation and survival. This compound is utilized in research settings to explore therapeutic strategies against various malignancies, contributing to the development of targeted cancer treatments.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1639014-72-4 |
| Applications | Tyrosine Kinase Inhibitor |
| Formula | C21H19ClF3N5O2 |
| Molecular Weight | 465.86 |
| Synonyms | Mifanertinib |
| SMILES | O=C(NC1=CC2=C(NC3=CC=C(C(Cl)=C3)F)N=CN=C2C=C1OC(F)F)/C=C/CN(C)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.