Fig. 1 · Structure
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Mefatinib
Tyrosine Kinase Inhibitor
Mefatinib is a potent tyrosine kinase inhibitor that exerts antineoplastic activity by inhibiting key signaling pathways involved in cell proliferation and survival. This compound is primarily utilized in cancer research, particularly for its efficacy against malignancies driven by aberrant tyrosine kinase signaling. Mefatinib's mechanism of action makes it a valuable tool for investigating therapeutic strategies targeting specific oncogenic pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1989592-50-8 |
| Applications | Tyrosine Kinase Inhibitor |
| Formula | C29H27ClF3N5O10 |
| Molecular Weight | 698.00 |
| Synonyms | Mifanertinib dimaleate |
| SMILES | OC(/C=C\C(O)=O)=O.O=C(NC1=CC2=C(NC3=CC=C(C(Cl)=C3)F)N=CN=C2C=C1OC(F)F)/C=C/CN(C)C.OC(/C=C\C(O)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.